Phleomycin D1

• Catalog Number: orb1983506
• Category: Small Molecules
• Description: Phleomycin D1 (PLM D1), a glycopeptide antibiotic in the Bleomycin/Phleomycin family, induces cell death by binding to and cleaving DNA [1] [2] [3].
• CAS Number: 11031-11-1
• Purity: 99.57%
• MW: 1427.52
• SMILES: [C@H]([C@H](NC(=O)C1=NC([C@@H](NC[C@@H](C(N)=O)N)CC(N)=O)=NC(N)=C1C)C(N[C@@H]([C@H]([C@@H](C(N[C@H](C(NCCC2=N[C@H](CS2)C3=NC(C(NCCCCNC(=N)N)=O)=CS3)=O)[C@@H](C)O)=O)C)O)C)=O)(O[C@H]4[C@@H](O[C@@H]5[C@@H](O)[C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O5)[C@@H](O)[C@H](O)[C@H](CO)O4)C6=CN=CN6
• Formula: C₅₅H₈₆N₂₀O₂₁S₂
• Biological Activity: Phleomycin D1 (PLM D1) is a glycopeptide antibiotic produced by a mutant strain of Streptomyces verticillus with antibacterial activity that disrupts the structural integrity of the bacterial double helix.Phleomycin D1 can be used to screen for transfected cells harboring the Sh ble gene.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.