Phentolamine

SKU: orb1299012

Description

Phentolamine mesylate is a non-selective alpha-adrenergic antagonist targeting both α1 and α2 receptors. It is widely used in cardiovascular research to study vasodilation, hypertension, and adrenergic signaling pathways in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 50-60-2
• MW: 281.35
• Purity: >99.99% (May vary between batches)
• Formula: C₁₇H₁₉N₃O
• SMILES: N(CC=1NCCN1)(C2=CC(O)=CC=C2)C3=CC=C(C)C=C3
• Target: Adrenergic Receptor
• Solubility: DMSO:22.5 mg/mL (79.97 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.11 mM)

Bioactivity

• In Vitro:
  Phentolamine Inhibits Angiogenesis in Vitro: Suppression of Proliferation Migration and Differentiation of Human Endothelial Cells

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

α1-adrenergic receptor, α2-adrenergic receptor, Phentolamine, Inhibitor, insulin secretion, erectile dysfunction, inhibit, orally active, Beta Receptor, Adrenergic Receptor, AdrenergicReceptor

Compound Identifiers

PubChem CID

5775