PGPC

SKU: orb1985089

Description

PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) is an oxidized phospholipid that serves as a concentration-dependent activator of peroxisome proliferator-activated receptors (PPARs). It is utilized in research to study lipid oxidation, inflammation, and metabolic signaling pathways in both cellular and animal models.

Key Properties

• CAS Number: 89947-79-5
• MW: 609.73
• Purity: 99.68% (May vary between batches)
• Formula: C₂₉H₅₆NO₁₀P
• SMILES: [C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCC(O)=O)=O
• Target: Others
• Solubility: Ethanol:20 mg/mL (32.8 mM);DMSO:1 mg/mL (1.64 mM)

Bioactivity

• In Vitro:
  PGPC activates peroxisome proliferator-activated receptor in a concentration-dependent manner. PGPC increases VCAM1 and E-selectin expression in human aortic endothelial cells, as well as HAEC binding by monocytes and polymorphonuclear neutrophils, in a concentration-dependent manner.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PGPC, 1-Palmitoyl-2-glutaryl phosphatidylcholine

Compound Identifiers

PubChem CID

46907872