PGD2-IN-1

SKU: orb1689963

Description

PGD2-IN-1 is a potent and selective DP receptor antagonist with an IC50 of 0.3 nM. This small molecule inhibitor of prostaglandin D2 signaling is a valuable research tool for studying allergic inflammation, asthma, and mast cell activation in both cellular and animal models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 885066-67-1
• MW: 460.35
• Purity: 99.46% (May vary between batches)
• Formula: C₂₃H₂₃Cl₂N₃O₃
• SMILES: COc1nc(NCCc2ccc(Cl)cc2Cl)cc(n1)-c1cccc(c1)C(C)(C)C(O)=O
• Target: Prostaglandin Receptor
• Solubility: 10% DMSO+90% Corn Oil:2 mg/mL (4.34 mM);DMSO:45 mg/mL (97.75 mM)

Bioactivity

• Target IC50:
  DP:0.3 nM.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, PGD2-inhibitor, PGD2 IN 1, PGD2(DP), PGD2IN1, PGD-2-IN-1, PGD2-IN-1, ProstaglandinReceptor, Prostaglandin Receptor

Compound Identifiers

PubChem CID

11669780