PG-901

SKU: orb3180560

Description

PG-901 is a full and selective MC5R agonist, exhibiting an EC50 of 0.072 nM for hMC5R. It also acts as a complete antagonist for hMC3R and hMC4R, with Kb values of 1.0 nM and 0.53 nM, respectively. Additionally, PG-901 significantly reduces the levels of cytokines (IL-1α, IL-1β, and IL-6), enhances glucose tolerance, lowers blood sugar, and mitigates retinal damage.

Key Properties

• Target: Interleukin,Melanocortin Receptor
• CAS Number: 322639-20-3
• MW: 1034.23
• Formula: C₅₃H₇₁N₁₃O₉
• SMILES: C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC5=C(C=C4)C=CC=C5)NC(=O)[C@]6(N(C(=O)[C@@H](NC([C@H](CCCC)NC(C)=O)=O)CC(=O)NCCCC[C@@H](C(N)=O)NC3=O)CCC6)[H]

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Interleukin,Melanocortin Receptor