PG-11047 2HCl

SKU: orb1819117

Description

PG-11047 2HCl is a pro-apoptotic small molecule compound used in biomedical research. Its applications include studies of lymphoma and prostate cancer, as well as investigations into genitourinary, immune, genetic, ocular, and hematological disorders, utilizing both in vitro and in vivo experimental models.

Research Area

Cell Biology

Key Properties

• MW: 329.35
• Purity: >99.99% (May vary between batches)
• Formula: C₁₄H₃₄Cl₂N₄
• SMILES: CCNCCCNCC=CCNCCCNCC.Cl.Cl
• Target: Apoptosis
• Solubility: DMSO:4.62 mg/mL (14.03 mM)

Bioactivity

• In Vitro:
  PG-11047 2HCl (13 nM-5 mM; 72 h) inhibits the growth of members of a broad range of mammary cell lineages, with basal-like cell lines being inhibited at lower concentrations than luminal cell lines. PG-11047 2HCl (0.3, 10, 300 μM; 48 h, 72 h) shows a significant reduction in S-phase fraction at doses that produce little apoptosis.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, CGC 11047, CGC-11047, CGC11047, CGC-11047 2HCl, PG 11047, PG11047, PG-11047 2HCl, PG-11047 2HCl(949933-50-0 Free base), PG-11047

Compound Identifiers

PubChem CID

171340832