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PfFAS-II inhibitor 1

SKU: orb2565550

Description

PfFAS-II Inhibitor 1 (Compound 3) is a potent and selective inhibitor of the Plasmodium falciparum FabI enzyme (IC50 = 0.63 µM), which is essential for the parasite's fatty acid biosynthesis. This small molecule is a valuable chemical tool for investigating the FAS-II pathway in malaria parasites through both in vitro enzymatic assays and in vivo antimalarial studies.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1459704-68-7
MW288.68
FormulaC15H9ClO4
SMILESO(C=1C=C2C(OC(=O)C=C2)=CC1)C3=C(O)C=C(Cl)C=C3
TargetParasite,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information