PF-8380 hydrochloride

SKU: orb1686465

Description

PF-8380 hydrochloride is a potent and selective autotaxin inhibitor with an IC50 of 2.8 nM in enzymatic assays and 101 nM in human whole blood. This tool compound is widely used in preclinical research to investigate lysophosphatidic acid (LPA) signaling in fibrosis, cancer, and neuropathic pain models, both in vitro and in vivo.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	2070015-01-7
MW	514.79
Formula	C₂₂H₂₂Cl₃N₃O₅
SMILES	Cl.Clc1cc(Cl)cc(COC(=O)N2CCN(CCC(=O)c3ccc4[nH]c(=O)oc4c3)CC2)c1
Target	PDE,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

78357775 ↗

Key Properties

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No computed properties available.

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