PF-7006

SKU: orb2665473

Description

PF-7006 is a potent and selective Mps1 kinase inhibitor (Ki=0.27 nM) that disrupts mitotic checkpoints, leading to apoptosis in cancer cells. It has demonstrated efficacy in breast cancer research models, both in vitro and in vivo, and shows altered cellular tolerance when combined with agents like Palbociclib.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2771955-09-8
• MW: 434.49
• Formula: C₂₂H₂₆N₈O₂
• SMILES: N#CC1=CNC2=NC(=NC(NC3CCOCC3)=C12)NC4=CC=C(N=C4C)N5CCOCC5
• Target: Apoptosis,Kinesin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155521427