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PF-562271 hydrochloride

PF-562271 hydrochloride

Catalog Number: orb1306208

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$ 180.00
Catalog Numberorb1306208
CategorySmall Molecules
DescriptionPF-562271 hydrochloride
CAS Number939791-41-0
Purity98.52%
MW543.95
SMILESCl.CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
FormulaC21H20F3N7O3S HCl
Biological ActivityPF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and > 100-fold selectivity against other protein kinases, except for some CDKs.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.