PF-562271 hydrochloride

• Catalog Number: orb1306208
• Category: Small Molecules
• Description: PF-562271 hydrochloride
• CAS Number: 939791-41-0
• Purity: 98.52%
• MW: 543.95
• SMILES: Cl.CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
• Formula: C₂₁H₂₀F₃N₇O₃S HCl
• Biological Activity: PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and > 100-fold selectivity against other protein kinases, except for some CDKs.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.