PF-3837

SKU: orb2665549

Description

PF-3837 is a potent and selective Mps1 kinase inhibitor (Ki=0.33 nM, IC50=5.5 nM) that induces cancer cell apoptosis by disrupting mitotic checkpoints. It is a valuable chemical probe for studying breast cancer mechanisms in both cellular and animal models of tumorigenesis.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2772910-13-9
• MW: 422.48
• Formula: C₂₁H₂₆N₈O₂
• SMILES: N#CC1=CNC2=NC(=NC(NC(C)(C)CO)=C12)NC3=CC=C(N=C3C)N4CCOCC4
• Target: Apoptosis,Kinesin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155511845