PF-3758309 dihydrochloride

SKU: orb1686056

Description

PF-3758309 dihydrochloride is a potent, reversible, and orally bioavailable ATP-competitive inhibitor of PAK4 (Kd=2.7 nM). It demonstrates functional cellular activity by inhibiting proliferation and anchorage-independent growth, inducing apoptosis, and causing cytoskeletal remodeling, making it a valuable tool for cancer research in both in vitro and in vivo models.

Research Area

Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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MW	563.55
Formula	C₂₅H₃₂Cl₂N₈OS
Target	PAK,Others,Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

PAK,Others,Apoptosis

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