PF-184

SKU: orb1744143

Description

PF-184 is a highly selective IKK-2 inhibitor (IC50 = 37 nM) with minimal activity against IKK-1 and numerous other kinases. It is a valuable research tool for investigating NF-κB signaling in inflammatory diseases, including applications in both in vitro and in vivo models of asthma and COPD.

Research Area

Signal Transduction

Key Properties

• MW: 619.09
• Formula: C₃₂H₃₂ClFN₆O₄
• SMILES: C[C@@]1([C@](C)(CN(C2=NC=C(Cl)C(C(NC(C=C3)=CC4=C3CCC(C(C(N)=O)=N5)=C4N5C6=CC=C(F)C=C6)=O)=C2)C1)CO)CO
• Target: IκB/IKK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57519531