PF-1367550

SKU: orb2802352

Description

PF-1367550 is a pan-JAK inhibitor that potently suppresses the release of the chemokines CXCL9, CXCL10, and CXCL11 from primary airway epithelial cells. This activity makes it a useful research tool for investigating JAK/STAT signaling and related inflammatory pathways in respiratory disease models, both in vitro and in vivo.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 319461-60-4
• MW: 354.41
• Formula: C₂₂H₁₈N₄O
• SMILES: OC=1C=CC(C=2C=CC=3C(=NNC3C2)C4=NC=5C=CC=CC5N4)=C(C1)CC
• Target: JAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135567293