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PF-07957472

PF-07957472

Catalog Number: orb2665015

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Catalog Numberorb2665015
CategorySmall Molecules
DescriptionPF-07957472 (Compound 4) is an orally effective inhibitor of the SARS-CoV-2 papain-like protease (PLpro). In NHBE cells infected with SARS-CoV-2, it demonstrated cytopathic effects with an EC50 of 13.9 nM. Additionally, PF-07957472 exhibited antiviral activity in a mouse-adapted COVID-19 infection model.
Purity98.00%
MW480.60
CAS Number3041047-51-9
FormulaC29H32N6O
SMILESO=C(NC1(C=2C=C(N=C3C=CC=CC32)C=4C=NN(C4)C)CC1)C5=CC(=CC=C5C)N6CCN(C)CC6
Storage-20°C
NoteFor research use only