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Catalog Number | orb2665015 |
---|---|
Category | Small Molecules |
Description | PF-07957472 (Compound 4) is an orally effective inhibitor of the SARS-CoV-2 papain-like protease (PLpro). In NHBE cells infected with SARS-CoV-2, it demonstrated cytopathic effects with an EC50 of 13.9 nM. Additionally, PF-07957472 exhibited antiviral activity in a mouse-adapted COVID-19 infection model. |
Purity | 98.00% |
MW | 480.60 |
CAS Number | 3041047-51-9 |
Formula | C29H32N6O |
SMILES | O=C(NC1(C=2C=C(N=C3C=CC=CC32)C=4C=NN(C4)C)CC1)C5=CC(=CC=C5C)N6CCN(C)CC6 |
Storage | -20°C |
Note | For research use only |