PF-06815345 hydrochloride

SKU: orb1745048

Description

PF-06815345 hydrochloride is a potent, orally bioavailable small molecule inhibitor of PCSK9 with an IC50 of 13.4 µM. It is a valuable research tool for studying PCSK9 biology and lipid metabolism, having demonstrated efficacy in reducing PCSK9 levels in mouse models.

Key Properties

• CAS Number: 2334434-49-8
• MW: 634.49
• Formula: C₂₇H₃₀Cl₂FN₉O₄
• SMILES: CN1C(=C(C=N1)C2=C(F)C=C(C(N(C3=C(Cl)C=CC=N3)[C@@H]4CCCNC4)=O)C=C2)C=5N([C@@H](OC(OCC)=O)C)N=NN5.Cl
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168006835