PF-06815345 hydrochloride

• Catalog Number: orb1745048
• Category: Small Molecules
• Description: PF-06815345 hydrochloride, an orally active potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), has an IC50 value of 13.4 μM. It significantly decreases in vivo PCSK9 levels in mice.
• CAS Number: 2334434-49-8
• Purity: 98.00%
• MW: 634.49
• SMILES: CN1C(=C(C=N1)C2=C(F)C=C(C(N(C3=C(Cl)C=CC=N3)[C@@H]4CCCNC4)=O)C=C2)C=5N([C@@H](OC(OCC)=O)C)N=NN5.Cl
• Formula: C₂₇H₃₀Cl₂FN₉O₄
• Biological Activity: PF-06815345 hydrochloride, an orally active potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), has an IC50 value of 13.4 μM. It significantly decreases in vivo PCSK9 levels in mice.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.