PF-06463922 acetate

SKU: orb1739420

Description

PF-06463922 acetate is a brain-penetrant, dual ALK/ROS1 inhibitor effective against crizotinib-resistant mutants. It is a research compound for studying oncogenic kinase signaling in NSCLC, with demonstrated activity in both cellular assays and preclinical in vivo models.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1924207-18-0
• MW: 466.46
• Formula: C₂₃H₂₃FN₆O₄
• SMILES: CC(O)=O.C[C@H]1Oc2cc(cnc2N)-c2c(CN(C)C(=O)c3ccc(F)cc13)nn(C)c2C#N
• Target: Others,Apoptosis,ROS Kinase,ALK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

124203822