PF-06426779

SKU: orb1691460

Description

PF-06426779 is a highly potent and selective small molecule inhibitor of IRAK4, demonstrating an IC50 of 0.3 nM. It is a valuable research tool for studying TLR/IL-1R signaling in autoimmune and inflammatory diseases, applicable in both cellular and animal models.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 1817628-40-2
• MW: 347.346
• Formula: C₁₇H₁₈FN₃O₄
• SMILES: COc1cc2c(OC[C@H]3NC(=O)[C@@H](F)[C@H]3C)nccc2cc1C(N)=O
• Target: IRAK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118414536