PF-06424439 methanesulfonate

• Catalog Number: orb1309264
• Category: Small Molecules
• Description: PF-06424439 methanesulfonate
• CAS Number: [1469284-79-4]
• Purity: 99.77%
• MW: 536.05
• SMILES: CS(O)(=O)=O.Clc1cnn(c1)C1(CC1)c1nc2ccc(nc2[nH]1)N1CCC[C@H](C1)C(=O)N1CCCC1
• Formula: C₂₃H₃₀ClN₇O₄S
• Biological Activity: PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM, demonstrates slow reversibility and time-dependent inhibition. It operates in a noncompetitive manner relative to the acyl-CoA substrate, marking its efficacy in targeting DGAT2.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.