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PF-06372222
Catalog Number: orb1987144
| Catalog Number | orb1987144 |
|---|---|
| Category | Small Molecules |
| Description | PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR). PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion. |
| CAS Number | 1407592-99-7 |
| Purity | 98.00% |
| MW | 515.53 |
| SMILES | [C@@H](NC=1C=CC(=NC1)N2C=C(C(F)(F)F)N=C2)(C3CC(C)(C)C3)C4=CC=C(C(NCCC(O)=O)=O)C=C4 |
| Formula | C26H28F3N5O3 |
| Biological Activity | PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR). PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
