PF-06291874

SKU: orb1296107

Description

PF-06291874 is a potent and orally bioavailable glucagon receptor antagonist. It is a valuable research tool for investigating glucagon receptor biology and has been utilized in both in vitro and in vivo studies related to metabolic disorders such as diabetes.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1393124-08-7
• MW: 503.51
• Purity: 99.27% (May vary between batches)
• Formula: C₂₆H₂₈F₃N₃O₄
• SMILES: CCC[C@H](Oc1cc(C)c(c(C)c1)-n1cc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O
• Target: Glucagon Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.97 mM);DMSO:30 mg/mL (59.58 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

clearance, bioavailability, oral, inhibit, Inhibitor, Glucagon receptor antagonists-4, Glucagon receptor antagonists4, Glucagon receptor antagonists 4, GlucagonReceptor, Glucagon Receptor, glucagon, GCGR, PF 06291874, PF06291874, PF-06291874

Compound Identifiers

PubChem CID

60151939