PF-06250112

SKU: orb1708710

Description

PF-06250112 is a potent and selective small molecule inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM. It also potently inhibits the related kinases BMX and TEC. This inhibitor is a valuable research tool for studying B-cell signaling pathways in both in vitro and in vivo models of autoimmune diseases and B-cell malignancies.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1609465-89-5
• MW: 438.43
• Formula: C₂₂H₂₀F₂N₆O₂
• SMILES: C(N)(=O)C=1C(=NN(C1N)[C@@H]2CN(C#N)CCC2)C3=CC=C(OC4=C(F)C=C(F)C=C4)C=C3
• Target: BTK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90118673