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PF-04822163

SKU: orb1699662

Description

PF-04822163 is a highly potent and selective PDE1 inhibitor with an IC50 of 2.4 nM. This compound is a valuable research tool for investigating PDE1-mediated signaling in cardiovascular and neurological research, as evidenced by its use in both cellular and animal model studies.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1798334-07-2
MW340.8
Purity>99.99% (May vary between batches)
FormulaC19H17ClN2O2
SMILESO(C)C=1C2=C(C(=NC=N2)[C@@H]3C=4C(CC3)=CC=C(Cl)C4)C=CC1OC
TargetPDE

Bioactivity

Target IC50
PDE4D3:7620 nM|PDE1B:2.4 nM|PDE1C:7 nM|PDE9A1:>30000 nM|PDE5A1:>30000 nM|PDE11A4:8257 nM|PDE1A:2 nM|PDE3A:>30000 nM|PDE2A:5895 nM|PDE7B:>29800 nM|PDE10A1:252 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PDE1, PF 04822163, PF 4822163, PF04822163, PF-04822163, PF4822163, PF-4822163

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    C19H17ClN2O2

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information