PF-04577806

SKU: orb1691988

Description

PF-04577806 is a potent, ATP-competitive inhibitor selective for multiple PKC isoforms, including PKCα, βI, βII, γ, and θ. It demonstrates efficacy in preclinical models, such as reversing retinal vascular leakage in diabetic rats, supporting its research use in studying PKC-related pathways in diabetes and vascular biology.

Research Area

Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1072100-81-2
• MW: 495.628
• Formula: C₂₆H₃₇N₇O₃
• SMILES: C[C@@H]1CN([C@@H](C)CN1CC1CCOCC1)C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C
• Target: PKC,Others,Phosphatase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25014995