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PF-00477736

SKU: orb1223534

Description

PF-00477736 (PF-477736) is a potent, selective, ATP-competitive inhibitor of Chk1 with Ki of 0.49 nM, also inhibits Chk2 (Ki=47 nM) and poorly inhibits CDK1 activity (Ki=9.9 uM).

Images & Validation

Key Properties

CAS Number952021-60-2
MW419.5
Purity>98% (HPLC)
FormulaC22H25N7O2
Targetc-Fms|Chk1|Chk2|VEGFR2|Yes

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

PF-00477736 (orb1223534)

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100 mg
200 mg
500 mg
2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 200.00
25 mg
$ 320.00