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Pevonedistat
Catalog Number: orb1300861
| Catalog Number | orb1300861 |
|---|---|
| Category | Small Molecules |
| Description | Pevonedistat |
| CAS Number | 905579-51-3 |
| Purity | 99.63% |
| MW | 443.52 |
| SMILES | NS(=O)(=O)OC[C@@H]1CC(C[C@@H]1O)n1ccc2c(NC3CCc4ccccc34)ncnc12 |
| Formula | C21H25N5O4S |
| Biological Activity | Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM). Pevonedistat can be used for the treatment of myelodysplastic syndromes (MDS) and also has antitumor activity. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
Pevonedistat hydrochloride [orb1706960]
99.31%
1160295-21-5
479.98
C21H26ClN5O4S
1 mg, 10 mg, 5 mg, 1 ml x 10 mm (in DMSO)
