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Perfluorotetradecanoic acid

SKU: orb2814096

Description

PFTeDA is a PPARγ antagonist that binds the human receptor's ligand-binding domain (IC50=22.8 µM; Kd=157.8 µM). This research chemical is used to study endocrine disruption, notably in models of Leydig cell toxicity involving oxidative stress and apoptosis, and for investigating adrenal steroidogenesis in vitro.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number376-06-7
MW714.11
FormulaC14HF27O2
SMILESO=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
TargetPPAR,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information