Pennogenin 3-O-beta-chacotrioside

SKU: orb1299161

Description

Pennogenin 3-O-beta-chacotrioside, a bioactive steroidal saponin from Paris polyphylla, exhibits anti-colorectal cancer activity by inducing autophagy. This is evidenced by its upregulation of key autophagy markers LC3 and Beclin-1 in vitro, supporting its use as a research tool for investigating autophagy-modulating pathways in oncology.

Research Area

Cell Biology

Key Properties

• CAS Number: 55916-52-4
• MW: 885.04
• Purity: 99.69%
• Formula: C₄₅H₇₂O₁₇
• SMILES: [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1(O)[C@H](C)[C@@]1(CC[C@@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
• Target: ATG,Autophagy
• Solubility: DMSO:140 mg/mL (158.18 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.13 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, inhibit, Inhibitor, Pennogenin 3-O-beta-chacotrioside, Pennogenin 3-O-β-chacotrioside, Pennogenin 3Obetachacotrioside, Pennogenin 3 O beta chacotrioside, Pennogenin 3-O-b-chacotrioside

Compound Identifiers

PubChem CID

21626520