Penitrem A

SKU: orb1708906

Description

Penitrem A is a tremorgenic indole-diterpenoid mycotoxin that acts as a selective BK channel blocker. It is widely used in neuroscience research to model tremor disorders in vivo and to study neurotransmitter release mechanisms, such as glutamate and GABA exocytosis, in vitro.

Research Area

Cancer Biology

Key Properties

• CAS Number: 12627-35-9
• MW: 634.21
• Purity: >98%
• Formula: C₃₇H₄₄ClNO₆
• SMILES: [H][C@@]12O[C@]11[C@]([H])(CC[C@]3(C)[C@@]4(C)c5[nH]c6cc(Cl)c7CC(=C)[C@@]8([H])C[C@@]9([H])[C@@]8(O)c7c6c5[C@@]([H])(OC9(C)C)[C@]4([H])CC[C@@]13O)O[C@@H]([C@@H]2O)C(C)=C
• Target: Ion channel
• Solubility: Soluble in DMSO (up to 6 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tremortin A; NSC354845

Compound Identifiers

PubChem CID

44450809