Pemetrexed tromethamine

SKU: orb1701815

Description

Pemetrexed tromethamine is a small molecule antifolate chemotherapeutic agent used in research models of non-small cell lung cancer and malignant pleural mesothelioma. It functions by inhibiting key folate-dependent enzymes, including thymidylate synthase, and is widely applied in both in vitro cytotoxicity assays and in vivo xenograft studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1851348-04-3
• MW: 705.72
• Formula: C₂₀H₂₁N₅O₆.2C₄H₁₁NO₃.2H₂O
• SMILES: OCC(CO)(N)CO.OC(CC[C@@H](C(O)=O)NC(C(C=C1)=CC=C1CCC2=CNC(NC(N)=N3)=C2C3=O)=O)=O.OCC(CO)(N)CO.O.O
• Target: Others,Endogenous Metabolite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135565678