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PDS-0330

SKU: orb1819116

Description

PDS-0330 is a micromolar-affinity, small-molecule inhibitor that binds directly and specifically to claudin-1. It disrupts the claudin-1/Src association, inhibiting colorectal cancer (CRC) progression and metastasis in research models, and exhibits chemosensitizing activity with characterized pharmacokinetics.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2904682-19-3
MW423.49
Purity99.93%
FormulaC25H17N3O2S
SMILESN(C(NC(=O)C1=CC2=C(C=C1)C=CC=C2)=S)C3=CC=C(C4=NC=5C(O4)=CC=CC5)C=C3
TargetGap Junction Protein,Tight Junction Protein,Others
SolubilityDMSO:1 mg/mL (2.36 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PDS 0330, PDS0330, PDS-0330, Claudin-1

Similar Products

  • PDS-0330 [orb1910788]

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    2904682-19-3

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    C25H17N3O2S

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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

PDS-0330 (orb1819116)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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1 mg
$ 90.00
5 mg
$ 160.00
10 mg
$ 240.00
25 mg
$ 400.00
50 mg
$ 560.00
100 mg
$ 750.00
200 mg
$ 1,000.00
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