PDpep1.3

SKU: orb3142361

Description

PDpep1.3 is a peptide inhibitor targeting α-synuclein, which disrupts the direct interaction between α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B). This disruption enables PDpep1.3 to restore the degradative functions of endosomes and lysosomes, reducing the levels and aggregation of α-synuclein, and safeguarding dopaminergic neurons from α-synuclein-induced degeneration. PDpep1.3 is useful for research on neurodegenerative diseases and protein-protein interactions.

Key Properties

• Target: Others
• CAS Number: 2942277-55-4
• MW: 1400.53
• Formula: C₅₉H₁₀₁N₁₇O₂₂
• SMILES: [C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)CC(C)C)=O)C)=O)CCCCN)=O)CC(C)C)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)(NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCC(O)=O)=O)CCC(O)=O)=O)[C@H](CC)C

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others