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PDM2

SKU: orb1221877

Description

PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.

Images & Validation

Key Properties

CAS Number688348-25-6
MW283.58
Purity>98% (HPLC)
FormulaC14H9Cl3
SMILESClc1ccc(cc1)\C=C\c1cc(Cl)cc(Cl)c1
TargetFAAH
SolubilityDMSO : 50 mg/mL 176.32 mM

Bioactivity

In Vitro
PDM2 (Compound 4b) exhibits a Ki of 1.2±0.4 nM for AhR and no affinity for estrogen receptor (ER), confirming that replacement of hydroxyl with chloride abolished binding on ER and increased dramatically the affinity for AhR.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

PDM2 (orb1221877)

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Available Sizes

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200 mg
500 mg
10 mg
$ 90.00
25 mg
$ 130.00
50 mg
$ 200.00
100 mg
$ 330.00