PDM11

SKU: orb1301710

Description

PDM11 is a small molecule aryl hydrocarbon receptor (AhR) antagonist with the chemical structure 1-[2-(4-chlorophenyl)-vinyl]-3,5-dimethylpyrazole. It is a research tool used in vitro and in vivo to study AhR signaling pathways in immunology, toxicology, and cancer research.

Research Area

Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 1032508-03-4
• MW: 274.74
• Purity: 99.88% (May vary between batches)
• Formula: C₁₆H₁₅ClO₂
• SMILES: C(=C/C1=CC=C(Cl)C=C1)\C2=CC(OC)=CC(OC)=C2
• Target: Phosphatase,Others,AhR
• Solubility: 10% DMSO+90% Corn Oil:1 mg/mL (3.64 mM);DMSO:10 mg/mL (36.4 mM)

Bioactivity

• Target IC50:
  BRD4(1):77 nM |BRD4(2):33 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth, AhR, inhibit, Inhibitor, PDM 11, PDM11, PDM-11

Compound Identifiers

PubChem CID

49799318