PDK-IN-2

SKU: orb2277735

Description

PDK-IN-2 is a potent PDK inhibitor (IC50 = 68 nM) that suppresses PDK1/4 expression, shifting cellular metabolism from glycolysis to mitochondrial oxidation and inducing mitochondrial apoptosis. It has demonstrated efficacy in reducing tumor growth in preclinical models, such as the 4T1 syngeneic mouse model, supporting its use in cancer metabolism research.

Research Area

Metabolism Research

Key Properties

• MW: 497.33
• Formula: C₁₇H₂₃AsCl₂N₂O₂S₂
• Target: Dehydrogenase,Mitochondrial Metabolism,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Dehydrogenase,Mitochondrial Metabolism,Others