PDHK1-IN-2

SKU: orb3028681

Description

PDHK1-IN-2 (Compound 24) is an ATP-competitive dual inhibitor of pyruvate dehydrogenase kinase 1/2 (PDHK1/2), with an IC50 of 0.007 μM for PDHK1 and 0.015 μM for PDHK2. PDHK1-IN-2 has the potential to regulate immune cell metabolism and correct mitochondrial dysfunction, making it a promising candidate for research in autoimmune diseases, inflammatory conditions, and cancer.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2870691-38-4
• MW: 468.567
• Formula: C₂₅H₃₃FN₆O₂
• SMILES: C(C)C1(C=2C(NC1=O)=C(NCC)C=C(F)C2)N3C[C@H](NC(=O)C4CC5(C4)CN(C#N)C5)CCC3
• Target: Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Dehydrogenase