PDEC-NB

SKU: orb1307323

Description

PDEC-NB is a disulfide-cleavable linker designed for constructing antibody-drug conjugates (ADCs). Its application facilitates targeted drug delivery research, enabling the study of payload release in both in vitro cellular assays and in vivo tumor models for cancer therapeutics development.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 874302-76-8
• MW: 352.385
• Purity: 99.66% (May vary between batches)
• Formula: C₁₄H₁₂N₂O₅S₂
• SMILES: O=C(OC1=CC=C([N+]([O-])=O)C=C1)OCCSSC2=NC=CC=C2
• Target: PROTAC Linker,ADC Linker
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (9.36 mM);DMSO:88 mg/mL (249.72 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PDEC-NB, PDEC NB, PDECNB, inhibit, Inhibitor, Cleavable, ADCLinker, ADC Linkers, ADC Linker, 4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate, Antibody-drug conjugates linkers

Compound Identifiers

PubChem CID

11638899