PDE5-IN-3

SKU: orb1687362

Description

PDE5-IN-3 is a potent, dual-targeting small molecule with low nanomolar PDE5 inhibition and moderate EGFR activity. It significantly suppresses the Wnt/β-catenin pathway and induces intrinsic apoptosis in HepG2 cells, demonstrating notable in vitro antitumor effects for oncology research.

Research Area

Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2538149-57-2
• MW: 448.27
• Formula: C₂₁H₁₄BrN₅O₂
• SMILES: O=C1C2=C(N(N=C2)C3=CC=C(Br)C=C3)NC(=N1)C=4C(OC)=NC5=C(C4)C=CC=C5
• Target: Wnt/beta-catenin,Others,EGFR,Apoptosis,PDE

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155806352