PDE4-IN-32

SKU: orb3210479

Description

PDE4-IN-32 (Compound B05) is a selective inhibitor of PDE4B and PDE4D with the capacity to penetrate the blood-brain barrier, exhibiting IC50 values of 13.7 nM and 23.8 nM, respectively. It aids in motor and cognitive recovery in MCAO/R mouse models, reduces cerebral edema, and is applicable in ischemic stroke research.

Key Properties

• CAS Number: 3080627-61-5
• MW: 320.34
• Formula: C₂₀H₁₆O₄
• SMILES: O=C1OCC=2C=C(C=CC12)C=3C=CC(OC)=C4OC(=CC43)C5CC5
• Target: PDE

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PDE