PDE3/4-IN-2

SKU: orb3134927

Description

PDE3/4-IN-2 is a potent dual PDE3/PDE4 inhibitor with IC50 values of 0.13 nM for PDE3A and 50 nM for PDE4B1. It is used to investigate PDE-related diseases such as asthma, COPD, sepsis, and nephritis. the dual-target activity of PDE3/4-IN-2 provides a mechanistic basis for dissecting cAMP regulation and inflammatory signaling pathways.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2857007-03-3
• MW: 503.59
• Purity: 99.99% (May vary between batches)
• Formula: C₂₈H₃₃N₅O₄
• SMILES: O=C1N=C(C=C2C=3C=C(OC)C(OC)=CC3CCN12)N(C=4C(=CC(=CC4C)C)C)CCN5C(=O)NCC5
• Target: PDE

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PDE