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PDE2-IN-1

SKU: orb3174072

Description

PDE2-IN-1 is a potent and orally active inhibitor of PDE2 with an IC50 of 0.6 μM, exhibiting neuroprotective properties. It regulates the PKA/CREB/BDNF signaling pathway by inhibiting PDE2. PDE2-IN-1 can improve memory deficits and cognitive impairments in okadai acid (OKA)-induced Alzheimer's disease (AD) mouse models and is useful for Alzheimer's disease research.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

TargetPDE,PKA

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information