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PDD00017272

SKU: orb1691375

Description

PDD00017272 (34f) is a highly potent and selective PARG inhibitor, demonstrating biochemical and cellular EC50 values in the low nanomolar range. This compound is a valuable chemical probe for investigating PARP biology and DNA damage response pathways in both cellular and in vivo cancer research models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1945950-20-8
MW531.67
Purity98.18% (May vary between batches)
FormulaC23H25N5O4S3
SMILESCc1ncc(Cn2c(=O)n(Cc3sc(C)nc3C)c3ccc(cc3c2=O)S(=O)(=O)NC2(C)CC2)s1
TargetOthers,Poly(ADP-ribose) Glycohydrolase (PARG)
SolubilityDMSO:20 mg/mL (37.62 mM);10% DMSO+90% Corn Oil:1 mg/mL (1.88 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PDD00017272, PDD-00017272, PDD 00017272, PARG
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 140.00
DispatchUsually dispatched within 5-10 working days
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