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AG-1517 HCl

SKU: orb1306664

Description

PD153035 hydrochloride is a potent and highly selective EGFR inhibitor with a Ki of 5.2 pM. It exhibits minimal activity against FGFR, PDGFR, InsR, CSF-1R, and Src. This compound is widely used in cancer research to study EGFR-driven signaling pathways in both cellular and animal models.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number153436-54-5
MW360.21
Purity>98%
FormulaC16H14BrN3O2
SMILESCOC1=CC2=NC=NC(NC3=CC(Br)=CC=C3)=C2C=C1OC
TargetKinase
SolubilitySoluble in DMSO (up to 5 mg/ml).

Bioactivity

Target IC50
EGFR:29 pM

Storage & Handling

StorageRT
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PD153,053; SU-5271; Z-252868

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Key Properties

No computed properties available.

Protocol Information

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5 mg
$ 200.00
25 mg
$ 460.00
DispatchUsually dispatched within 5-10 working days
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