PD1-PDL1-IN-4

SKU: orb3211549

Description

PD1-PDL1-IN-4 (compound 19) is a potent and orally bioavailable PD1-PDL1 inhibitor that modulates the TIGIT and PD-1 signaling pathways. It promotes the proliferation of CD8+ T cells and splenocytes in mice and inhibits tumor growth in a CT26 syngeneic colon adenocarcinoma mouse model. PD1-PDL1-IN-4 is applicable for colon cancer research.

Key Properties

• CAS Number: 2007110-15-6
• MW: 419.43
• Formula: C₁₉H₂₅N₅O₆
• SMILES: [C@@H](CC1=CC=C(O)C=C1)(NC(=O)N2[C@H](C(O)=O)CCC2)C3=NC([C@H]([C@H](C)O)N)=NO3
• Target: PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PD-1/PD-L1