PD-L1/HDAC3-IN-1

SKU: orb3135043

Description

PD-L1/HDAC3-IN-1 (PH3) is a dual inhibitor of PD-L1 and HDAC3, exhibiting IC50 values of 89.4 nM for PD-1/PD-L1 and 107 nM for HDAC3. It induces apoptosis and arrests the cell cycle in the G0/G1 phase. PD-L1/HDAC3-IN-1 demonstrates anticancer activity both in vitro and in vivo.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Immunology & Inflammation; Epigenetics & Chromatin, Molecular Biology

Key Properties

• Target: HDAC,PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HDAC,PD-1/PD-L1