PD-1/PD-L1-IN-52

SKU: orb2664919

Description

PD-1/PD-L1-IN-52 (Compound Ⅲ-5) is an orally bioavailable small molecule inhibitor that blocks the PD-1/PD-L1 interaction with an IC50 of 109.9 nM. It demonstrates in vivo antitumor efficacy, showing 49.6% tumor growth inhibition in a humanized PD-1 MC38 colon carcinoma mouse model, supporting its use in immuno-oncology research.

Research Area

Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation

Key Properties

• Target: PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PD-1/PD-L1