PD-1/PD-L1-IN-49

SKU: orb3028142

Description

PD-1/PD-L1-IN-49 (compound 1c) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 77 nM. This compound can activate Jurkat T cells and effectively block the PD-1/PD-L1 immune checkpoint.

Research Area

Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation

Key Properties

• MW: 492.567
• Formula: C₂₇H₃₂N₄O₅
• SMILES: CC1=C(C=CC=C1NC(=O)C2=NC=C(C=C2)CNC(CO)(CO)CO)C3=CC4=C(C=C3)N(CCO4)C
• Target: PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PD-1/PD-L1