PD-1/PD-L1-IN-47

SKU: orb2664365

Description

PD-1/PD-L1-IN-47 is a small molecule inhibitor with enhanced selectivity for the PD-1/PD-L1 interaction under acidic conditions, such as those found in the tumor microenvironment. This pH-dependent activity, coupled with a favorable toxicity profile, makes it a valuable tool for investigating cancer immunotherapy in both cellular assays and in vivo models.

Research Area

Cancer Biology; Immunology & Inflammation

Key Properties

• CAS Number: 1137341-95-7
• MW: 484.45
• Formula: C₂₂H₂₈O₁₂
• SMILES: O(CC(C)C1(O)CC(=O)OC1)[C@@H]2O[C@H](COC(/C=C/C3=CC(O)=C(O)C=C3)=O)[C@@H](O)[C@H](O)[C@H]2O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23928151