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PD-1/PD-L1-IN-44

SKU: orb3134108

Description

PD-1/PD-L1-IN-44 (Compound 22) selectively inhibits the PD-1/PD-L1 protein with an IC50 of 1.21 nM. In animal models, PD-1/PD-L1-IN-44 effectively suppressed tumor growth and increased CD8+ cell infiltration without exhibiting toxicity.

Research Area

Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

FormulaC34H30N2O6
TargetPD-1/PD-L1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information