PD-1/PD-L1-IN-33

SKU: orb1944202

Description

PD-1/PD-L1-IN-33 (Compound N11) is a potent small molecule inhibitor that blocks the PD-1/PD-L1 interaction with an IC50 of 6.3 nM. This blockade enhances T-cell function and tumor infiltration, demonstrating immunomodulatory and antitumor activity in both cellular assays and in vivo cancer models for research applications.

Research Area

Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 2975602-78-7
• MW: 425.53
• Formula: C₂₆H₂₇N₅O
• SMILES: C(NC(CO)(C)C)C1=CC2=C(C(N3C=4C(CC3)=C(C=CC4)C5=CC=CC=C5)=NC=N2)N=C1
• Target: PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510602